Description
A slow, tight binding, competitive aminopeptidase (AP) inhibitor, first described as an inhibitor of AP-A (glutamyl AP; IC50 = 0.54 µg/ml) but not of AP-B (arginine AP); also inhibits AP-N (AP-M, alanyl AP; Ki = 20-200 nM), leucyl-cystinyl AP (Ki = 20-220 nM), and endoplasmic reticulum AP 1 (Ki = 41.8 µM)
Formal name: N-[(2S,3R)-3-amino-2-hydroxy-5-methyl-1-oxohexyl]-L-valyl-L-valyl-L-aspartic acid, monohydrochloride
Synonyms:
Molecular weight: 511
CAS: 100938-10-1
Purity: ≥95%
Formulation: A crystalline solid
Product Type|Biochemicals|Small Molecule Inhibitors|Peptidases & Proteases||Research Area|Cell Biology|Proteolysis|Cytosolic & Secreted Proteases||Research Area|Cell Biology|Proteolysis|Lysosomal Proteases
