A glucokinase activator (EC50 = 60 nM in an enzyme assay); decreases plasma glucose levels in an oral glucose tolerance test in an ob/ob mouse model of diabetes when administered orally at 3-30 mg/kg

AM2394 – 10 mg

Brand:
Cayman
CAS:
1442684-77-6
Storage:
-20
UN-No:
Non-Hazardous - /

AM2394 is an activator of glucokinase with an EC50 value of 60 nM in an enzyme assay in the presence of glucose.{52555} Oral administration of AM2394 (3-30 mg/kg) decreases plasma glucose levels in an oral glucose tolerance test in an ob/ob mouse model of diabetes.  

 

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Description

A glucokinase activator (EC50 = 60 nM in an enzyme assay); decreases plasma glucose levels in an oral glucose tolerance test in an ob/ob mouse model of diabetes when administered orally at 3-30 mg/kg

Formal name: N-[6′-(2-hydroxy-2-methylpropoxy)-4-[(5-methyl-3-pyridinyl)oxy][3,3′-bipyridin]-6-yl]-N’-methyl-urea

Synonyms: 

Molecular weight: 423.5

CAS: 1442684-77-6

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Activators|Kinases||Research Area|Endocrinology & Metabolism|Carbohydrate Metabolism||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes

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