An antispasmodic agent; suppresses contractions induced by potassium or ACh in isolated guinea pig detrusor smooth muscle; blocks spontaneous and vagal-stimulated colonic motility in rabbits; reduces the number of abdominal contractions induced by 5-HTP or high volume rectal distension in rats at 75 μg/animal

Alverine (citrate) – 5 g

Brand:
Cayman
CAS:
5560-59-8
Storage:
4
UN-No:
Non-Hazardous - /

Alverine is an antispasmodic agent.{46289} It suppresses contractions induced by potassium or acetylcholine (ACh), but increases spontaneous contractions, in isolated guinea pig detrusor smooth muscle. Alverine blocks spontaneous and vagal-stimulated colonic motility in rabbits.{46290} Alverine (75 μg/animal) reduces the number of abdominal contractions induced by 5-hydroxy-L-tryptophan (5-HTP; Item No. 20539) or high volume (1.6 ml) rectal distension in rats.{46291} Formulations containing alverine have been used in the treatment of functional gut disorders.  

 

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Description

An antispasmodic agent; suppresses contractions induced by potassium or ACh in isolated guinea pig detrusor smooth muscle; blocks spontaneous and vagal-stimulated colonic motility in rabbits; reduces the number of abdominal contractions induced by 5-HTP or high volume rectal distension in rats at 75 μg/animal

Formal name: N-ethyl-N-(3-phenylpropyl)-benzenepropanamine, mono-2-hydroxy-1,2,3-propanetricarboxylate

Synonyms:  NSC 35459

Molecular weight: 473.6

CAS: 5560-59-8

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals||Research Area|Neuroscience|Pain Research

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