A natural mycotoxin that shows mutagenic activity against S. typhimurium and inhibits human topoisomerase II and bacterial gyrase; completely inhibits replication of HIV-1 virus at 2.2 µM in a cell-based assay

Altertoxin I – 1 mg

Brand:
Cayman
CAS:
56258-32-3
Storage:
-20
UN-No:
De Minimis - 3462 / 6.1

Altertoxin I is a natural mycotoxin first isolated from fungi of the genus Alternaria. It is a hydroxyperylenequinone that shows mutagenic activity against S. typhimurium and inhibits human topoisomerase II and bacterial gyrase.{33238,33239} Altertoxin I completely inhibits replication of HIV-1 virus at 2.2 µM in a cell-based assay.{33237}  

 

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Description

A natural mycotoxin that shows mutagenic activity against S. typhimurium and inhibits human topoisomerase II and bacterial gyrase; completely inhibits replication of HIV-1 virus at 2.2 µM in a cell-based assay

Formal name: (1S,12aR,12bS)-1,2,11,12,12a,12b-hexahydro-1,4,9,12a-tetrahydroxy-3,10-perylenedione

Synonyms:  Dihydroalterperylenol

Molecular weight: 352.3

CAS: 56258-32-3

Purity: ≥97%

Formulation: A powder

Product Type|Biochemicals|Antivirals||Product Type|Biochemicals|Small Molecule Inhibitors|MMPs||Product Type|Biochemicals|Small Molecule Inhibitors|Topoisomerases||Product Type|Biochemicals|Toxins|Mycotoxins||Research Area|Infectious Disease|Viral Diseases|HIV & AIDS||Research Area|Toxicology

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