An inhibitor of Cdk1

Aloisine RP106 – 10 mg

Brand:
Cayman
CAS:
496864-15-4
Storage:
-20
UN-No:
Non-Hazardous - /

Aloisine is an inhibitor of Cdk1/cyclin B, Cdk5/p25, and GSK3 (IC50s = 0.70, 1.5, and 0.92 µM, respectively).{38576} It is a derivative of the aloisines A and B, which competitively inhibit ATP binding to the catalytic subunit of CDKs and GSKs.  

 

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Description

An inhibitor of Cdk1, Cdk5, and GSK3 (IC50s = 0.70, 1.5, and 0.92 µM, respectively); a derivative of the aloisines A and B

Formal name: 7-butyl-6-(4-methoxyphenyl)-5H-pyrrolo[2,3-b]pyrazine

Synonyms: 

Molecular weight: 281.4

CAS: 496864-15-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Kinase Inhibitors|CDKs||Product Type|Biochemicals|Kinase Inhibitors|GSK3||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cell Biology|Cell Cycle||Research Area|Cell Biology|Cell Signaling

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