A product of purine and uric acid metabolism; Urinary levels of allantoin are increased in APP/tau mice prior to the onset of Alzheimer’s disease symptoms but not during the early/middle stage of the disease

Allantoin – 100 g

Brand:
Cayman
CAS:
97-59-6
Storage:
-20
UN-No:
Non-Hazardous - /

Allantoin is a product of purine and uric acid metabolism.{45992} It is formed through oxidation of uric acid by urate oxidase in most mammals but is formed only through non-enzymatic oxidation by free radicals in humans. Urinary levels of allantoin are increased prior to the onset of Alzheimer’s disease symptoms in mice expressing mutations in amyloid precursor protein and tau (APP/tau) but not during the early/middle stage of the disease, indicating its potential use as a biomarker for predicting Alzheimer’s disease onset.{45993} Due to the formation of allantoin by free radicals in humans, increased urinary levels are a potential biomarker for oxidative stress status.{45992}  

 

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SKU: 30204 - 100 g Category:

Description

A product of purine and uric acid metabolism; Urinary levels of allantoin are increased in APP/tau mice prior to the onset of Alzheimer’s disease symptoms but not during the early/middle stage of the disease, indicating a potential use as a biomarker for predicting Alzheimer’s disease onset; increased urinary levels are a potential biomarker for oxidative stress status in humans

Formal name: N-(2,5-dioxo-4-imidazolidinyl)-urea

Synonyms:  (±)-Allantoin|5-Ureidohydantoin|NSC 7606|SD 101

Molecular weight: 158.1

CAS: 97-59-6

Purity: ≥95%

Formulation: A crystalline solid

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