A natural retinoid that associates with CRBP-I and CRBP-II (Kds = 50 and 90 nM

all-trans-Retinal – 100 mg

Brand:
Cayman
CAS:
116-31-4
Storage:
-20
UN-No:
Non-Hazardous - /

all-trans-Retinal is a natural retinoid that is derived from vitamin A. It is the oxidation product of all-trans-retinol and associates with cellular retinol-binding protein-I (CRBP-I) and CRBP-II (Kds = 50 and 90 nM, respectively), which are involved in the intracellular transport of retinol.{14372} all-trans-Retinal is also an intermediate of the phototransduction pathway of photoreceptors, including rhodopsin and bacterial opsins.{29923} As a chemically reactive aldehyde, all-trans-retinal can form toxic conjugates with proteins and lipids, leading to degeneration of the retina.{29923}  

 

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Description

A natural retinoid that associates with CRBP-I and CRBP-II (Kds = 50 and 90 nM, respectively), which are involved in the intracellular transport of retinol; an intermediate of the phototransduction pathway of photoreceptors; can form toxic conjugates with proteins and lipids, leading to degeneration of the retina

Formal name: retinal

Synonyms:  Retinaldehyde|Vitamin A aldehyde

Molecular weight: 284.4

CAS: 116-31-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products||Research Area|Neuroscience|Ophthalmology

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