Inhibitor of P450 isoforms CYP1A1

Alizarin – 50 g

Brand:
Cayman
CAS:
72-48-0
Storage:
22
UN-No:
Non-Hazardous - /

Alizarin is a small molecule inhibitor of cytochrome P450 isoforms CYP1A1, CYP1A2, and CYP1B1 (IC50s = 6.2, 10, and 2.7 µM, respectively).{22084} Alizarin acts as an antioxidant against iodophenol-derived phenoxyl radicals, superoxide anion radicals, and lipid peroxidation in rat liver microsomes.{34371} It also reduces hepatic content of thiobarbituric acid-reactive substances and serum levels of alanine aminotransferase in poisoned rats.{34371} Alizarin is also used as a red dye to stain bacteria, human adipose-derived stem cells, multipotent adult progenitor cells, skin, hair, and keratin fibers.{22804,34372,34370}  

 

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SKU: 11676 - 50 g Category:

Description

Inhibitor of P450 isoforms CYP1A1, CYP1A2, and CYP1B1; antioxidant activity in rats; reduces hepatic content of reactive substances and serum aminotransferases in poisoned rats; a small molecule red dye

Formal name: 1,2-dihydroxy-9,10-anthracenedione

Synonyms:  CI-58000|NSC 7212

Molecular weight: 240.2

CAS: 72-48-0

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Product Type|Biochemicals|Small Molecule Inhibitors|Cytochrome P450||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Lipid Peroxidation||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen

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