A corticosteroid; reduces cutaneous anaphylaxis reactions induced by tuberculin or albumin in mice when administered topically (20 μl of a 0.1% solution); inhibits androgen-dependent cytochrome P450 activity and the O-depropylation activity of 7-alkoxy-coumarin O-dealkylase in a dose-dependent manner in male rats; has no effect on hepatic drug metabolism in female rats or mice of both sexes

Alclometasone Dipropionate – 25 mg

Brand:
Cayman
CAS:
66734-13-2
Storage:
-20
UN-No:
Non-Hazardous - /

Alclometasone dipropionate (ACM) is a corticosteroid.{41325} It reduces cutaneous anaphylaxis reactions induced by tuberculin or albumin in mice when administered topically (20 μl of a 0.1% solution). ACM also inhibits androgen-dependent cytochrome P450 activity and the O-depropylation activity of 7-alkoxy-coumarin O-dealkylase in a dose-dependent manner in male rats but has no effect on hepatic drug metabolism in female rats or mice of both sexes.{41326} Formulations containing ACM have been used to treat radiation and allergic contact dermatitis.  

 

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SKU: 23901 - 25 mg Category:

Description

A corticosteroid; reduces cutaneous anaphylaxis reactions induced by tuberculin or albumin in mice when administered topically (20 μl of a 0.1% solution); inhibits androgen-dependent cytochrome P450 activity and the O-depropylation activity of 7-alkoxy-coumarin O-dealkylase in a dose-dependent manner in male rats; has no effect on hepatic drug metabolism in female rats or mice of both sexes

Formal name: 7α-chloro-11β-hydroxy-16α-methyl-17,21-bis(1-oxopropoxy)-pregna-1,4-diene-3,20-dione

Synonyms:  ACM|Alclometasone 17,21-Dipropionate|SCH 22219

Molecular weight: 521

CAS: 66734-13-2

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Lipids|Sterol Lipids||Product Type|Biochemicals|Small Molecule Inhibitors|Cytochrome P450||Research Area|Immunology & Inflammation|Allergy||Research Area|Toxicology|Drug Metabolism|Cytochrome P450

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