A neutral

Alamethicin F50 – 1 mg

Brand:
Cayman
CAS:
56165-93-6
Storage:
-20
UN-No:
Non-Hazardous - /

Alamethicin F50 is a peptaibol isolated from Trichoderma.{41167} It is a polymer of 20 amino acids that includes modified and non-proteinogenic amino acids.{41168} Alamethicin F50 is a mixture of 13 different peptides, with the most abundant designated as alamethicin F50/5. Alamethicin F50 forms voltage-dependent ion channels in lipid membranes and acts as a lytic agent.{41170,41169} It induces lysis of leukocytes (IC50 = 54 and 80 μM for rat mast cells and mouse spleen lymphocytes, respectively) and exhibits antibacterial activity against a panel of 8 mollicutes (MICs = 1.56-12.5 μM).  

 

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SKU: 23141 - 1 mg Category:

Description

A neutral, linear peptaibol isolated from Trichoderma sp.; induces formation of voltage-dependent ion channels in lipid membranes; acts as a lytic (IC50 = 54 and 80 μM for rat mast cells and mouse spleen lymphocytes); exhibits antibacterial activity against mollicutes (MICs = 1.56-12.5 μM)

Formal name: 18-L-glutamine-alamethicin I

Synonyms:  18-L-Glutamine Alamethicin I

Molecular weight: 1,963.30

CAS: 56165-93-6

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Infectious Disease|Bacterial Diseases

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