AIF Polyclonal Antibody – 500 µl

Brand:
Cayman
Storage:

Immunogen: Synthetic peptide from an internal region of human AIF • Host: Rabbit • Cross Reactivity: (+) Human, rat, and mouse AIF; other species not tested • Applications: WB • AIF is a highly conserved mitochondrial protein with roles in redox-biochemistry and apoptosis.  

 

SKU: 160773- 500 µl Category:

Description

Apoptosis-inducing factor (AIF) is a highly conserved mitochondrial protein with roles in redox-biochemistry and apoptosis.{10026,8815} Apoptosis is a controlled process of cell death necessary for proper physiological development and maintenance. Loss of mitochondrial membrane potential results in the release of several proteins critical to the acceleration of apoptosis.{6767} When AIF is released from the mitochondrial intermembrane space it migrates to the nucleus to initiate chromatin condensation and DNA cleavage.{7005,10024,9739} AIF is recognized by immunoblotting at 67 kDa in most tissues and cell lines.


Synonyms: Apoptosis-Inducing Factor|Programmed Cell Death Protein 8

Immunogen: Synthetic peptide from an internal region of human AIF

Formulation: 500 µl of peptide affinity purified polyclonal antibody

Isotype:

Applications: WB

Origin: Animal/Rabbit

Stability: 730 days


Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cell Biology|Cell Death|Apoptosis||Research Area|Cell Biology|Mitochondrial Biology