An inhibitor of EGF receptor kinase with an IC50 value of 2.4 µM in the human epidermoid carcinoma cell line A431

AG-213 – 10 mg

Brand:
Cayman
CAS:
122520-86-9
Storage:
-20
UN-No:
Non-Hazardous - /

Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds that act as PTK blockers. PTK inhibitors which preferentially inhibit the epidermal growth factor (EGF) receptor kinase block EGF-dependent cell proliferation.{14963} AG-213 is an inhibitor of epidermal growth factor (EGF) receptor kinase with an IC50 value of 2.4 µM in the human epidermoid carcinoma cell line A431.{14963}  

 

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SKU: 10010314 - 10 mg Category:

Description

An inhibitor of EGF receptor kinase with an IC50 value of 2.4 µM in the human epidermoid carcinoma cell line A431

Formal name: 2-cyano-3-(3,4-dihydroxyphenyl)-2E-propenethioamide

Synonyms:  Tyrphostin 47|Tyrphostin AG-213

Molecular weight: 220.2

CAS: 122520-86-9

Purity: ≥97%

Formulation: A crystalline solid

Product Type|Biochemicals|Kinase Inhibitors|EGFR/ErbB/HER Family||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cancer|Cell Signaling|Growth Factor Receptor Signaling

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