Description
Adropin is a 76 amino acid secreted peptide expressed in the brain, liver, and plasma and is encoded by the energy homeostasis associated gene.{16583} It is highly conserved in mammals, and is involved in glucose homeostasis and lipid metabolism.{16583} Plasma levels of adropin decrease with age and have been associated with metabolic disorders such as dyslipidemia and insulin resistance.{21988} Adropin is involved in post-transcriptional activation of eNOS, the up-regulation of VEGFR2, and activation of the ERK1/2 pathway.{21989} Adropin’s involvement in endothelial cells results in increased proliferation and migration, and decreased permeability and apoptosis.{21989} Western blot detects adropin at 14-17 kDa in an over-expression cell lysate, and at 25 kDa for SUMO-tagged adropin recombinant protein.
Synonyms: Energy Homeostasis-Associated Protein
Immunogen: Human adropin amino acids 34-76
Formulation: 200 µg of protein G-purified IgG
Isotype: IgG1
Applications: ELISA and WB
Origin:
Stability: 365 days
Application|ELISA||Application|Western Blot||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Cell Biology|Cell Death|Apoptosis||Research Area|Cell Biology|Cell Signaling|ERK/MAPK Signaling||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Dyslipidemias
