A histamine H1 receptor antagonist (Ki = 10 nM in COS-7 cells expressing the human receptor); completely inhibits response to histamine in guinea pigs when administered at a dose of 1 mg/kg

Acrivastine – 5 mg

Brand:
Cayman
CAS:
87848-99-5
Storage:
-20
UN-No:
Non-Hazardous - /

Acrivastine is a histamine H1 receptor antagonist with a Ki value of 10 nM in COS-7 cells expressing the human receptor.{39413} In vivo, acrivastine (1 mg/kg) completely inhibits response to histamine in guinea pigs.{39412} Formulations containing acrivastine have been used for the treatment of seasonal allergies and hay fever.  

 

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SKU: 24021 - 5 mg Category:

Description

A histamine H1 receptor antagonist (Ki = 10 nM in COS-7 cells expressing the human receptor); completely inhibits response to histamine in guinea pigs when administered at a dose of 1 mg/kg,

Formal name: (2E)-3-[6-[(1E)-1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propen-1-yl]-2-pyridinyl]-2-propenoic acid

Synonyms:  BW 0270C|BW A825C

Molecular weight: 348.4

CAS: 87848-99-5

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Immunology & Inflammation|Allergy

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