A neonicotinoid insecticide; an agonist of insect nAchRs; activates nAchRs containing N. lugens α1 and rat β2 subunits (EC50 = 67 µM in X. laevis oocytes); leads to sexual and aggressive behaviors in adult male offspring after administration to pregnant mice (1 mg/kg); decreases anxiety-like behavior of adult male offspring in the light-dark transition test (1 and 10 mg/kg)

Acetamiprid – 10 mg

Brand:
Cayman
CAS:
135410-20-7
Storage:
-20
UN-No:
De Minimis - 2811 / 6.1

Acetamiprid is a neonicotinoid insecticide that acts as an agonist of insect nicotinic acetylcholine receptors (nAchRs). It activates nAchRs containing N. lugens α1 and rat β2 subunits with an EC50 value of 67 µM in X. laevis oocytes.{42008} Acetamiprid administered to pregnant mice at a dose of 1 mg/kg leads to sexual and aggressive behaviors in adult male offspring while doses of 1 and 10 mg/kg decrease anxiety-like behavior of adult male offspring in the light-dark transition test.{42009} Formulations containing acetamiprid have been used to control sucking insects on crops and pets.  

 

Available on backorder

Add to quotes
SKU: 24129 - 10 mg Category:

Description

A neonicotinoid insecticide; an agonist of insect nAchRs; activates nAchRs containing N. lugens α1 and rat β2 subunits (EC50 = 67 µM in X. laevis oocytes); leads to sexual and aggressive behaviors in adult male offspring after administration to pregnant mice (1 mg/kg); decreases anxiety-like behavior of adult male offspring in the light-dark transition test (1 and 10 mg/kg)

Formal name: (1E)-N-[(6-chloro-3-pyridinyl)methyl]-N’-cyano-N-methyl-ethanimidamide

Synonyms: 

Molecular weight: 222.7

CAS: 135410-20-7

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Ion Channel Modulation||Product Type|Biochemicals|Pesticides|Insecticides||Research Area|Neuroscience|Behavioral Neuroscience|Anxiety||Research Area|Toxicology|Environmental|Agriculture

Related products

  • A potent inhibitor of Cdk2/cyclin E with an IC50 value of 0.1 µM; also inhibits Cdk7/cyclin H

    (R)-Roscovitine – 5 mg

    Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. (R)-Roscovitine is a potent inhibitor of Cdk2/cyclin E with an IC50 value of 0.1 µM.{14988} It also inhibits Cdk7/cyclin H, Cdk5/p35, and cell division cycle (cdc)/cyclin B with IC50 values of 0.49, 0.16, and 0.65 µM, respectively.{14987,14988,14991} (R)-Roscovitine inhibits the growth of rapidly proliferating cells with an average IC50 value of 15.2 µM against a panel of 19 human tumor cell lines.{14988} In murine models of polycystic kidney disease, (R)-roscovitine effectively inhibited disease progression at doses of 50-100 mg/kg.{14564}  

     

    Brand:
    Cayman
    SKU:10009569 - 5 mg

    Available on backorder

    Add to quotes
    Add to quotes
    View product page
  • A powerful effector in both the TetR and revTetR transcriptional regulator systems

    Anhydrotetracycline (hydrochloride) – 100 mg

    The tetracycline repressor (TetR) is a transcriptional regulator which normally binds tightly to its palindromic tetO operator DNA, blocking gene expression.{17508} Tet causes the repressor to dissociate from the DNA, allowing transcription to occur. A novel reverse TetR (revTetR) requires tetracycline as a co-repressor to bind tetO and block transcription.{17509,17510} Anhydrotetracycline (hydrochloride) is a powerful effector in both the tetracycline repressor (TetR) and reverse TetR (revTetR) systems, binding the Tet repressor 35-fold more strongly than Tet.{17508,17511} Moreover, anhydrotetracycline poorly binds the 30S ribosomal subunit, compared to Tet,{17512} so it does not act as a general inhibitor of translation and is a poor antibiotic. Perhaps related to this, the concentration of anhydrotetracycline that inhibits eukaryotic cell growth is more than a 1,000-fold above the dose that alters transcription through TetR.{17508}  

     

    Brand:
    Cayman
    SKU:10009542 - 100 mg

    Available on backorder

    Add to quotes
    Add to quotes
    View product page
  • PtdIns-(3

    PtdIns-(3,4,5)-P3-biotin (sodium salt) – 50 µg

    The PtdIn phosphates play an important role in the generation and transduction of intracellular signals.{8344,4096,14518} PtdIns-(3,4,5)-P3-biotin is an affinity probe which allows the PIP3 to be detected through an interaction with the biotin ligand. This design allows PtdIns-(3,4,5)-P3-biotin to serve as a general probe for any protein with a high affinity binding interaction with inositol-(3,4,5)-triphosphate phospholipids, such as phosphatidylinositol 3-kinase, PTEN, or PH-domain-containing proteins.  

     

    Brand:
    Cayman
    SKU:10009531 - 50 µg

    Available on backorder

    Add to quotes
    Add to quotes
    View product page
  • A zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers

    1,2-Dipalmitoyl-sn-glycero-3-PC – 100 mg

    1,2-Dipalmitoyl-sn-glycero-3-PC (DPPC) is a zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers, bilayers, and liposomes for use in a variety of applications.{14480,24261,14478,14479} It has been used in the formation of proteoliposomes for implantation of γ-glutamyl transpeptidase into human erythrocyte membranes.{14478} Incorporation of glycosphingolipid antigens into DPPC-containing liposomes increases the immunogenicity of the antigens in mice.{14479}  

     

    Brand:
    Cayman
    SKU:10009473 - 100 mg

    Available on backorder

    Add to quotes
    Add to quotes
    View product page