An active metabolite of procainamide; prevents hypoxia-induced ventricular fibrillation in mice and decreases aconitine-induced arrhythmia in dogs; decreases lipid droplet area by greater than 50% in SK-Hep1 cells when used in high-fat medium without inducing cytotoxicity

Acecainide (hydrochloride) – 1 g

Brand:
Cayman
CAS:
34118-92-8
Storage:
-20
UN-No:
Non-Hazardous - /

Acecainide is an active metabolite of the class III antiarrhythmic procainamide.{45230} It is formed from procainamide via hepatic N-acetyltransferases.{45232} Acecainide prevents hypoxia-induced ventricular fibrillation in mice and decreases arrhythmia induced by aconitine in dogs.{45230} Acecainide (10 µM), when used in high-fat medium, decreases lipid droplet area by greater than 50% in SK-Hep1 cells without inducing cytotoxicity but does not affect lipid droplets in primary mouse hepatocytes.{45233}  

 

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SKU: 27312 - 1 g Category:

Description

An active metabolite of procainamide; prevents hypoxia-induced ventricular fibrillation in mice and decreases aconitine-induced arrhythmia in dogs; decreases lipid droplet area by greater than 50% in SK-Hep1 cells when used in high-fat medium without inducing cytotoxicity

Formal name: 4-(acetylamino)-N-[2-(diethylamino)ethyl]-benzamide, monohydrochloride

Synonyms:  N-Acetylprocainamide

Molecular weight: 313.8

CAS: 34118-92-8

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Cardiovascular System|Heart|Arrhythmia||Research Area|Lipid Biochemistry||Research Area|Toxicology|Drug Metabolism|Drug Metabolites

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