A fluorogenic substrate whose amino acids YVAD have been shown to be a preferred cleavage site for caspase-1 and -4

Ac-YVAD-AFC – 1 mg

Brand:
Cayman
CAS:
219137-85-6
Storage:
-20
UN-No:
Non-Hazardous - /

Ac-YVAD-AFC is a substrate whose amino acids YVAD have been shown to be a preferred cleavage site for caspase-1 and -4.{7213,22862} Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm.  

 

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Description

A fluorogenic substrate whose amino acids YVAD have been shown to be a preferred cleavage site for caspase-1 and -4

Formal name: N-​acetyl-​​L-​​tyrosyl-​L-​​valyl-​​L-​alanyl-​​N-​​[2-​​oxo-​​4-​​(trifluoromethyl)​-​2H-​1-​​benzopyran-​​7-​yl]​-​L-​​α-​asparagine

Synonyms:  Ac-Tyr-Val-Ala-Asp-7-amino-4-Trifluoromethlcoumarin|Caspase-1 Substrate VI (Fluorogenic)

Molecular weight: 719.7

CAS: 219137-85-6

Purity: ≥95%

Formulation: A crystalline solid

Application|Enzyme Activity||Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Enzyme Substrates||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Research Area

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