Ac-PAL-AMC – 10 mg

Brand:
Cayman
CAS:
1431362-79-6
Storage:
-20
UN-No:
Non-Hazardous - /

Ac-PAL-AMC is a fluorogenic substrate for the β1i/LMP2 subunit of the 20S immunoproteasome.{42571,42570} Upon cleavage, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify the activity of the β1i/LMP2 subunit of the 20S immunoproteasome. Ac-PAL-AMC is selective for the immunoproteasome over the constitutive proteasome. AMC displays excitation/emission maxima of 351/430 nm, respectively.  

 

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SKU: 26592 - 10 mg Category:

Description

,A fluorogenic substrate for the 20S proteasome; AMC is released upon enzymatic cleavage by the β1i/LMP2 subunit of the immunoproteasome and its fluorescence can be used to quantify enzyme activity; selective for the immunoproteasome over the constitutive proteasome; 351/430 nm, respectively

Formal name: 1-acetyl-L-prolyl-L-alanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-leucinamide

Synonyms:  Acetyl-Pro-Ala-Leu-7-amino-4-Methylcoumarin|Ac-Pro-Ala-Leu-AMC

Molecular weight: 498.6

CAS: 1431362-79-6

Purity: ≥95%

Formulation: A solid

Application|Enzyme Activity||Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Enzyme Substrates||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Product Type|Biochemicals|Peptides|Peptide Hormones||Research Area|Cell Biology|Proteolysis|Ubiquitin/Proteasome System

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