A fluorogenic substrate for caspase-9; AMC is released upon cleavage by caspase-9 and its fluorescence can be used to quantify caspase-9 activity; ex/em = 340-360/440-460 nm

Ac-LEHD-AMC (trifluoroacetate salt) – 500 µg

Brand:
Cayman
CAS:
292633-16-0
Storage:
-20
UN-No:
Non-Hazardous - /

Ac-LEHD-AMC is a fluorogenic substrate for caspase-9.{41518} Upon cleavage by caspase-9, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify caspase-9 activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.  

 

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SKU: 24569 - 500 µg Category:

Description

A fluorogenic substrate for caspase-9; AMC is released upon cleavage by caspase-9 and its fluorescence can be used to quantify caspase-9 activity; ex/em = 340-360/440-460 nm, respectively

Formal name: N-acetyl-L-leucyl-L-α-glutamyl-L-histidyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine, trifluoroacetate salt

Synonyms:  Ac-Leu-Glu-His-Asp-AMC|Caspase-9 Substrate

Molecular weight: 711.7

CAS: 292633-16-0

Purity: ≥95%

Formulation: A lyophilized powder

Application|Enzyme Activity||Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Enzyme Substrates||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Research Area|Cell Biology|Cell Death|Apoptosis||Research Area|Cell Biology|Proteolysis|Cytosolic & Secreted Proteases

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