Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp – 1 mg

Brand:
Cayman
CAS:
824405-61-0
Storage:
-20
UN-No:
Non-Hazardous - /

Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp is a fluorescence-quenched peptide substrate for human neutrophil elastase (kcat/Km = 531 mM-1s-1).{26783} Enzymatic peptide hydrolysis disrupts the Abz:EDDnp donor-acceptor pair allowing fluorescence measurement of Abz (ex = 320 nm; em = 420 nm).  

 

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Description

A fluorescence-quenched peptide substrate for human neutrophil elastase (ex = 320 nm; em = 420 nm)


Formal name: N-(2-aminobenzoyl)-L-alanyl-L-prolyl-L-α-glutamyl-L-α-glutamyl-L-isoleucyl-L-methionyl-L-arginyl-L-arginyl-N1-[2-[(2,4-dinitrophenyl)amino]ethyl]-L-glutamamide

Synonyms: 

Molecular weight: 1,456.60

CAS: 824405-61-0

Purity: ≥95%

Formulation: A solid


Application|Enzyme Activity||Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Enzyme Substrates||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Research Area|Cell Biology|Proteolysis|Cytosolic & Secreted Proteases||Research Area|Cell Biology|Proteolysis|Lysosomal Proteases||Research Area|Immunology & Inflammation|Innate Immunity