An NHH carbamate that inhibits the Wnt-deacylating enzyme NOTUM (IC50 = 13 nM); preserves Wnt3A signaling in the presence of NOTUM (EC50 = 89 nM in a cell-based reporter assay)

ABC99 – 5 mg

Brand:
Cayman
CAS:
2331255-53-7
Storage:
-20
UN-No:
Non-Hazardous - /

ABC99 is an N-hydroxyhydantoin (NHH) carbamate that inhibits the Wnt-deacylating enzyme NOTUM (IC50 = 13 nM).{35387} It preserves Wnt3A signaling in the presence of NOTUM (EC50 = 89 nM in a cell-based reporter assay).  

 

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SKU: 25858 - 5 mg Category:

Description

An NHH carbamate that inhibits the Wnt-deacylating enzyme NOTUM (IC50 = 13 nM); preserves Wnt3A signaling in the presence of NOTUM (EC50 = 89 nM in a cell-based reporter assay)

Formal name: 7-(4-chlorobenzyl)-1,3-dioxohexahydroimidazo[1,5-a]pyrazin-2(3H)-yl-2,3-dihydro-4H-benzo[b][1,4]oxazine-4-carboxylate

Synonyms: 

Molecular weight: 456.9

CAS: 2331255-53-7

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Cell Biology|Cell Signaling|Wnt Signaling

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