An inhibitor that blocks the integrin-ligand interaction between LFA-1 and ICAM-1 (IC50 = 35 nM); inhibits adhesion of JY-8 cells to ICAM-1-coated microtiter plates (IC50 = 44 nM)

A286982 – 10 mg

Brand:
Cayman
CAS:
280749-17-9
Storage:
-20
UN-No:
Non-Hazardous - /

A286982 is an inhibitor that blocks the integrin-ligand interaction between leukocyte function-associated antigen-1 (LFA-1) and intercellular adhesion molecule-1 (ICAM-1; IC50 = 35 nM).{46441} It inhibits adhesion of JY-8 cells to ICAM-1-coated microtiter plates (IC50 = 44 nM).  

 

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SKU: 27646 - 10 mg Category:

Description

An inhibitor that blocks the integrin-ligand interaction between LFA-1 and ICAM-1 (IC50 = 35 nM); inhibits adhesion of JY-8 cells to ICAM-1-coated microtiter plates (IC50 = 44 nM)

Formal name: (2E)-1-(4-acetyl-1-piperazinyl)-3-[4-[[2-(1-methylethyl)phenyl]thio]-3-nitrophenyl]-2-propen-1-one

Synonyms: 

Molecular weight: 453.6

CAS: 280749-17-9

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals||Research Area|Immunology & Inflammation|Adaptive Immunity||Research Area|Immunology & Inflammation|Innate Immunity

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