An indole-derived CB that acts as a full agonist at both the CB1 and CB2 receptors (Kis = 4.6 and 0.31 nM

A-834735 – 1 mg

Brand:
Cayman
CAS:
895155-57-4
Storage:
-20
UN-No:
Non-Hazardous - /

A-834735 is an indole-derived cannabinoid (CB) with a 3-tetramethylcyclopropylmethanone substituent. It acts as a full agonist at both the central CB1 and peripheral CB2 receptors in rat with Ki values of 4.6 and 0.31 nM, respectively. and EC50 values of 12 and 0.21 nM, respectively.{22084} A-834735 readily crosses the blood-brain barrier, dose-dependently reversing thermal hyperalgesia without adverse side effects in a rat neuropathic pain model.{22084}  

 

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SKU: 11163 - 1 mg Category:

Description

An indole-derived CB that acts as a full agonist at both the CB1 and CB2 receptors (Kis = 4.6 and 0.31 nM, respectively; EC50s = 12 and 0.21 nM, respectively); dose-dependently reverses thermal hyperalgesia without adverse side effects in a rat neuropathic pain model

Formal name: [1-[(tetrahydro-2H-pyran-4-yl)methyl]-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)-methanone

Synonyms: 

Molecular weight: 339.5

CAS: 895155-57-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Drugs of Abuse||Research Area|Forensic Chemistry & Toxicology|Cannabinoids|Synthetic Cannabinoids

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