Description
A 15-LO-1 inhibitor (IC50 = 0.19 µM); decreases LPS- and IFN-γ-induced NF-ĸB activity in RAW-Blue™ cells at 0.2, 1, and 5 µM; reduces LPS- and IFN-γ-induced increases in Nos2 expression and lipid peroxidation in RAW 264.7 cells at 5 µM
Formal name: 6-chloro-3-[(1E)-3-[[(2-methoxyphenyl)methyl]amino]-3-oxo-1-propen-1-yl]-1H-indole-2-carboxylic acid, ethyl ester
Synonyms:
Molecular weight: 412.9
CAS: 2349374-37-2
Purity: ≥95%
Formulation: A crystalline solid