9-deoxy-9-methylene-16

9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 – 10 mg

Brand:
Cayman
CAS:
61263-35-2
Storage:
-20
UN-No:
De Minimis - 1231 / 3

9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 (Meteneprost) is a potent analog of prostaglandin E2 (PGE2; Item No. 14010) with an extended half-life in vivo. In combination with various other prostaglandin derivatives, it results in the termination of first trimester pregnancy in monkeys. A single intramuscular injection containing 0.5 mg of meteneprost and 7.5 mg of 17-phenyl trinor PGF1α is very effective in terminating early pregnancy.{4692} This prostaglandin mixture is ineffective on monkeys in their third trimester of pregnancy.{4692} Meteneprost, when compared to PGE2 and PGF1α, in monkey and rat, does not result in unwanted side effects such as fever or gastrointestinal problems.{4692,464}  

 

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Description

9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 (Meteneprost) is a potent analog of prostaglandin E2 (PGE2; Item No. 14010) with an extended half-life in vivo. In combination with various other prostaglandin derivatives, it results in the termination of first trimester pregnancy in monkeys. A single intramuscular injection containing 0.5 mg of meteneprost and 7.5 mg of 17-phenyl trinor PGF1α is very effective in terminating early pregnancy.{4692} This prostaglandin mixture is ineffective on monkeys in their third trimester of pregnancy.{4692} Meteneprost, when compared to PGE2 and PGF1α, in monkey and rat, does not result in unwanted side effects such as fever or gastrointestinal problems.{4692,464}

Formal name: 9-methylene-11α,15R-dihydroxy-16,16-dimethyl-prosta-5Z,13E-dien-1-oic acid

Synonyms:  9-deoxy-9-methylene-16,16-dimethyl PGE2|Meteneprost

Molecular weight: 378.6

CAS: 61263-35-2

Purity: ≥98%

Formulation: A solution in methyl acetate

Product Type|Biochemicals|Lipids|Prostaglandins||Research Area|Endocrinology & Metabolism|Reproductive Biology||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway

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