The most abundant isoprostane product formed during lipid peroxidation; detected after CCl4-induced oxidative damage to hepatic tissue and has been found elevated in the urine

8,12-iso-iPF2α-VI – 25 µg

Brand:
Cayman
CAS:
1445349-99-4
Storage:
-20
UN-No:
De Minimis - 1648 / 3

8,12-iso-iPF2α-VI is an isoprostane produced by non-enzymatic, free radical-induced peroxidative damage to membrane lipids. It is the most abundant isoprostane product that is formed during lipid peroxidation and is used as a biomarker for oxidative stress.{9408} 8,12-iso-iPF2α-VI is detected after CCl4-induced oxidative damage to hepatic tissue and has been found elevated in the urine, blood, and cerebrospinal fluid of patients with Alzheimer’s disease.{16731,10961,16633}  

 

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Description

The most abundant isoprostane product formed during lipid peroxidation; detected after CCl4-induced oxidative damage to hepatic tissue and has been found elevated in the urine, blood, and CSF of patients with Alzheimer’s disease

Formal name: (12α)-5,9α,11α-trihydroxy-prosta-6E,14Z-dien-1-oic acid

Synonyms:  12-iso-5,6E,14Z-PGF2α|12-iso-5,6E,14Z-Prostaglandin F2α|8,12-iso-Isoprostane-F2α-VI

Molecular weight: 354.5

CAS: 1445349-99-4

Purity: ≥95%

Formulation: A solution in acetonitrile

Product Type|Biochemicals|Lipids|Isoprostanes||Product Type|Biochemicals|Lipids|Prostaglandins||Research Area|Lipid Biochemistry|Reactive O2/N2 Pathways||Research Area|Neuroscience|Neurodegenerative Disorders|Alzheimer’s Disease||Research Area|Oxidative Stress & Reactive Species|Lipid Peroxidation

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