Description
8,11,14-Eicosatriynoic acid is an inhibitor of prostaglandin and leukotriene biosynthesis as well as arachidonic acid induced platelet aggregation.{14705} It inhibits cyclooxygenase (IC50 = 14 µM), human 12-lipoxygenase (IC50 = 0.46 µM), 5-lipoxygenase (IC50 = 25 µM) and the actions of slow-reacting substance of anaphylaxis (SRS-A) (IC50 = 10 µM).{14704,14706}
Formal name: 8,11,14-eicosatriynoic acid
Synonyms: 8,11,14-ETI
Molecular weight: 300.4
CAS: 34262-64-1
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Lipids|Fatty Acids||Product Type|Biochemicals|Small Molecule Inhibitors|Cyclooxygenases||Product Type|Biochemicals|Small Molecule Inhibitors|Lipoxygenases||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway||Research Area|Lipid Biochemistry|Lipoxygenase Pathways