A cell-impermeable fluorescent pH probe; ex/em= 403 and 450 nm

8-Hydroxypyrene-1,3,6-trisulfonic Acid (sodium salt) – 1 g

Brand:
Cayman
CAS:
6358-69-6
Storage:
-20
UN-No:
Non-Hazardous - /

8-Hydroxypyrene-1,3,6-trisulfonic acid (HPTS) is a cell-impermeable fluorescent pH probe.{52382,22782} It displays excitation maxima of 403 and 450 nm, the intensities of which decrease and increase, respectively, as pH increases from 5 to 9 and an emission maximum of 510 nm.{52382} HPTS has been used in excitation ratio imaging to monitor changes in and measure the pH of endocytosed liposomes, acidic organelles, or the cytoplasm in live cell applications.{52382,22782} It is sensitive to fluorescence quenching by viologens, which can be reversed in the presence of glucose or other monosaccharides, and has been used as a glucose and carbohydrate sensor.{37199}  

 

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SKU: 30080 - 1 g Category:

Description

A cell-impermeable fluorescent pH probe; ex/em= 403 and 450 nm, the intensities of which decrease and increase, respectively, as pH increases from 5 to 9/510 nm; has been used in excitation ratio imaging to monitor changes in and measure the pH of endocytosed liposomes, acidic organelles, or the cytoplasm in live cell applications; sensitive to fluorescence quenching by viologens, which can be reversed in the presence of glucose or other monosaccharides, and has been used as a glucose and carbohydrate sensor

Formal name: 8-hydroxy-1,3,6-pyrenetrisulfonic acid, trichloride

Synonyms:  HPTS|Pyranine

Molecular weight: 524.4

CAS: 6358-69-6

Purity: ≥95%

Formulation: A crystalline solid

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