A cell-permeable analog of cGMP that preferentially activates cGMP-dependent protein kinase; 1 µM-0.1 mM inhibits acetylcholine-induced increases in intracellular calcium concentrations

8-bromo-Cyclic GMP (sodium salt) – 50 mg

Brand:
Cayman
CAS:
51116-01-9
Storage:
-20
UN-No:
Non-Hazardous - /

8-bromo-Cyclic GMP (8-bromo-cGMP) is a cell-permeable analog of cGMP that exhibits greater resistance to hydrolysis by phosphodiesterases than its parent compound. It preferentially activates cGMP-dependent protein kinase.{25938} At 1 µM-0.1 mM, 8-bromo-cGMP can inhibit acetylcholine-induced increases in intracellular calcium concentrations.{25937}  

 

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Description

A cell-permeable analog of cGMP that preferentially activates cGMP-dependent protein kinase; 1 µM-0.1 mM inhibits acetylcholine-induced increases in intracellular calcium concentrations

Formal name: 8-bromo-guanosine cyclic 3′,5′-(hydrogen phosphate), monosodium salt

Synonyms:  ​​8-bromo-cGMP|8-bromo Guanosine 3’,5’-cyclic monophosphate

Molecular weight: 447.1

CAS: 51116-01-9

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Activators|Kinases||Research Area|Cell Biology|Cell Signaling|cGMP Signaling

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