A coumarin with diverse biological activities; reduces A23187-induced release of PGE2 and LTC4 in isolated mouse peritoneal macrophages; active against S. aureus

7-Methoxycoumarin – 5 g

Brand:
Cayman
CAS:
531-59-9
Storage:
-20
UN-No:
Non-Hazardous - /

7-Methoxycoumarin is a coumarin that has been found in S. oblongifolia and has diverse biological activities.{57033,57034,57035} It reduces the release of prostaglandin E2 (PGE2; Item No. 14010) and leukotriene C4 (LTC4; Item No. 20210) induced by A23187 (Item No. 110160) in isolated mouse peritoneal macrophages.{57033} 7-Methyoxycoumarin is active against S. aureus, S. epidermidis, B. subtilis, S. lutea, and V. cholera (MICs = 0.5, 0.75, 0.75, 0.75, and 0.5 mg/ml, respectively).{57034} In vivo, 7-methoxycoumarin (3.5 and 7 mg/kg) reduces formalin-induced paw licking and biting responses in mice.{57035}  

 

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SKU: 30857 - 5 g Category:

Description

A coumarin with diverse biological activities; reduces A23187-induced release of PGE2 and LTC4 in isolated mouse peritoneal macrophages; active against S. aureus, S. epidermidis, B. subtilis, S. lutea, and V. cholera (MICs = 0.5, 0.75, 0.75, 0.75, and 0.5 mg/ml, respectively); reduces formalin-induced paw licking and biting responses in mice at 3 and 7.5 mg/kg

Formal name: 7-methoxy-2H-1-benzopyran-2-one

Synonyms:  Ayapanin|Gerniarin|Herniarin|Methylumbelliferone|NSC 404559

Molecular weight: 176.2

CAS: 531-59-9

Purity: ≥98%

Formulation: A solid

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