An active metabolite of paclitaxel; exhibits properties comparable to paclitaxel on both cells and in vitro microtubule polymerization

7-epi Paclitaxel – 500 µg

Brand:
Cayman
CAS:
105454-04-4
Storage:
-20
UN-No:
Non-Hazardous - /

7-epi Paclitaxel is an active metabolite of paclitaxel (Taxol; Item No. 10461), a widely used chemotherapeutic compound.{32610} It is the major metabolite found in cells, although 6α-hydroxy paclitaxel (6α-hydroxy Taxol; Item No. 10009027) is the major biliary metabolite of paclitaxel in humans.{32610,32609} 7-epi Paclitaxel exhibits properties comparable to paclitaxel on both cells and in vitro microtubule polymerization.{32609}  

 

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Description

An active metabolite of paclitaxel; exhibits properties comparable to paclitaxel on both cells and in vitro microtubule polymerization

Formal name: (αR,βS)-β-(benzoylamino)-α-hydroxy-benzenepropanoic acid, (2aR,4R,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester

Synonyms:  7-epi Taxol

Molecular weight: 853.9

CAS: 105454-04-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Microtubule Dynamics||Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Cancer|Cell Cycle|G1||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Cancer|Cell Signaling|Abl family & Bcr-Abl Signaling||Research Area|Cancer|Cell Signaling|p53 Signaling||Research Area|Cancer|Transcription Factors|p53||Research Area|Cell Biology|Cytoskeleton & Motor Proteins

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