An oxysterol; formed by enzymatic and non-enzymatic oxidation of cholesterol; induces apoptosis and cell death of HUVECs in vitro; increased plasma levels positively correlate with mortality in coronary heart disease in human males

7β-hydroxy Cholesterol – 1 mg

Brand:
Cayman
CAS:
566-27-8
Storage:
-20
UN-No:
Non-Hazardous - /

7β-hydroxy Cholesterol is an oxysterol formed by enzymatic and non-enzymatic oxidation of cholesterol.{36765} It is the primary oxysterol found in LDL and induces apoptosis and cell death of human umbilical vein endothelial cells (HUVECs) in vitro in a concentration-dependent manner. Increased plasma levels of 7β-hydroxy cholesterol positively correlate with mortality in coronary heart disease in human males.{36766}  

 

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Description

An oxysterol; formed by enzymatic and non-enzymatic oxidation of cholesterol; induces apoptosis and cell death of HUVECs in vitro; increased plasma levels positively correlate with mortality in coronary heart disease in human males

Formal name: (3β,7β)-cholest-5-ene-3,7-diol

Synonyms:  7β-Hydroxycholesterol|7β-OHC

Molecular weight: 402.7

CAS: 566-27-8

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Lipids|Sterol Lipids||Research Area|Cardiovascular System|Cardiovascular Diseases|Coronary Artery Disease||Research Area|Cardiovascular System|Lipids & Lipoproteins|Lipoproteins||Research Area|Cardiovascular System|Vasculature||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Dyslipidemias||Research Area|Lipid Biochemistry|Reactive O2/N2 Pathways||Research Area|Lipid Biochemistry|Sterol Lipids

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