A reduced form of folic acid that serves as a cofactor in methyltransferase reactions and is the major one-carbon carrier in one carbon metabolism; important for the synthesis of thymidine for incorporation into DNA or the synthesis of purines

(6R,S)-5,6,7,8-Tetrahydrofolic Acid (hydrochloride) – 1 mg

Brand:
Cayman
CAS:
150731-85-4
Storage:
-20
UN-No:
Non-Hazardous - /

(6R,S)-5,6,7,8-Tetrahydrofolic acid (THFA), the reduced form of folic acid, serves as a cofactor in methyltransferase reactions and is the major one-carbon carrier in one carbon metabolism.{29515} Its metabolites participate in the synthesis of thymidine for incorporation into DNA or the synthesis of purines, as well as in the formation of methionine, which can be converted to the ubiquitous methyl donor, S-adenosylmethionine (Item No. 13956).{29515} THFA has also been used to study the activation of metabolite-binding riboswitches.{29514}  

 

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Description

A reduced form of folic acid that serves as a cofactor in methyltransferase reactions and is the major one-carbon carrier in one carbon metabolism; important for the synthesis of thymidine for incorporation into DNA or the synthesis of purines, as well as for the formation of methionine, which can be converted to the ubiquitous methyl donor, SAM

Formal name: N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid, trihydrochloride

Synonyms:  Tetrahydrofolate|THFA

Molecular weight: 554.8

CAS: 150731-85-4

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals||Research Area|Endocrinology & Metabolism|Cofactors & Vitamins||Research Area|Epigenetics, Transcription, & Translation|RNA, DNA, & Protein Synthesis||Research Area|Epigenetics, Transcription, & Translation|Writers

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