Description
A potent CYP3A4 inhibitor (IC50s = 0.30 ppm in a cell-free assay, 0.33 µM in HL7 human liver cells, and 0.22 µM in S9 human intestine cells); inhibits the transport of talinolol, a P-gp/ABCB1 transporter substrate, across Caco-2 cell monolayers (IC50 = 0.7 µM); has insecticidal properties (5 µg/cm2 leads to 100% mortality of adult olive fruit flies)
Formal name: 4-[[(2E)-5-(3,3-dimethyl-2-oxiranyl)-3-methyl-2-penten-1-yl]oxy]-7H-furo[3,2-g][1]benzopyran-7-one
Synonyms: Epoxybergamottin
Molecular weight: 354.4
CAS: 206978-14-5
Purity: ≥98%
Formulation: A crystalline solid
Application|Mass Spectrometry||Product Type|Biochemicals|Natural Products|Coumarins||Product Type|Biochemicals|Pesticides|Insecticides||Product Type|Biochemicals|Small Molecule Inhibitors|Cytochrome P450||Product Type|Biochemicals|Small Molecule Inhibitors|MMPs||Research Area|Toxicology|Drug Metabolism|Cytochrome P450
