A photolabile H+-donor used in fluorescence imaging; releases acid when excited at 405 nm; has been used for fluorescence imaging

6-Nitroveratraldehyde – 5 g

Brand:
Cayman
CAS:
20357-25-9
Storage:
-20
UN-No:
Non-Hazardous - /

6-Nitroveratraldehyde is a photolabile H+-donor that releases acid when excited at 405 nm.{36196} It has been used for fluorescence imaging, in conjunction with the pH sensitive fluorescent probe cSNARF1, to study nuclear proton dynamics, acid venting from cancer cells, and hemoglobin-restricted diffusion in the cytoplasm of red blood cells.{36196,36197,36198} 6-Nitroveratraldehyde has also been used as a precursor for [18F]fluoride displacement reactions in the synthesis of NCA 6-[18F]fluoro-L-dopa that is used in positron emission tomography (PET) studies of dopaminergic systems.{36199}  

 

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Description

A photolabile H+-donor used in fluorescence imaging; releases acid when excited at 405 nm; has been used for fluorescence imaging, in conjunction with pH sensitive fluorescent probe cSNARF1, to study nuclear proton dynamics, acid venting from cancer cells, and hemoglobin-restricted diffusion in the cytoplasm of red blood cells; has been used as a precursor for [18F]fluoride displacement reactions in the synthesis of NCA 6-[18F]fluoro-L-dopa

Formal name: 4,5-dimethoxy-2-nitro-benzaldehyde

Synonyms:  DMNB|NSC 65590

Molecular weight: 211.2

CAS: 20357-25-9

Purity: ≥98%

Formulation: A crystalline solid

Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection||Research Area|Cancer||Research Area|Neuroscience

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