5(S)

5(S),6(R)-11-trans DiHETE – 50 µg

Brand:
Cayman
CAS:
129263-59-8
Storage:
-80
UN-No:
De Minimis - 1170 / 3

5(S),6(R)-11-trans DiHETE is a C-11 double bond isomer of 5(S),6(R)-DiHETE that is formed by the enzymatic isomerization of 5(S),6(R)-DiHETE by a membrane bound factor.{14924} 5(S),6(R)-11-trans DiHETE has been found in rat kidney homogenates and is potentially formed by the epoxide hydrolase pathway in this tissue.{14924} The isomerase activity responsible for the conversion of leukotriene B4 (LTB4) to 6-trans LTB4 in rat kidney homogenates has also been implicated in its formation.{14925} 5(S),6(R)-11-trans DiHETE is not a substrate for soybean lipoxygenase.{14924} The biological activity of 5(S),6(R)-11-trans DiHETE has not been reported.  

 

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SKU: 10009628 - 50 µg Category:

Description

5(S),6(R)-11-trans DiHETE is a C-11 double bond isomer of 5(S),6(R)-DiHETE that is formed by the enzymatic isomerization of 5(S),6(R)-DiHETE by a membrane bound factor.{14924} 5(S),6(R)-11-trans DiHETE has been found in rat kidney homogenates and is potentially formed by the epoxide hydrolase pathway in this tissue.{14924} The isomerase activity responsible for the conversion of LTB4 to 6-trans LTB4 in rat kidney homogenates has also been implicated in its formation.{14925} 5(S),6(R)-11-trans DiHETE is not a substrate for soybean lipoxygenase.{14924} The biological activity of 5(S),6(R)-11-trans DiHETE has not been reported.

Formal name: 11-trans-5S,6R-dihydroxy-7E,9E,11E,14Z-eicosatetraenoic acid

Synonyms: 

Molecular weight: 336.5

CAS: 129263-59-8

Purity: ≥95%

Formulation: A solution in ethanol

Product Type|Biochemicals|Lipids|Hydroxy/Hydroperoxy/ Epoxy/Oxo Eicosanoids||Research Area|Lipid Biochemistry|Cytochrome P450 Pathways||Research Area|Lipid Biochemistry|Lipoxygenase Pathways

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