5,7-Dihydroxychromone – 5 mg

Brand:
Cayman
CAS:
31721-94-5
Storage:
-20
UN-No:
Non-Hazardous - /

5,7-Dihydroxychromone is a flavone decomposition product that has been found in A. hypogaea and has diverse biological activities, including antimicrobial, antioxidant, and neuroprotective properties.{48623,48624} It reduces radial growth of the soil pathogenic fungi R. solani and S. rolfsii (IC50s = 18 and 26 µM, respectively) but has no effect on soil pathogenic bacteria of the genus Bradyrhizobium.{48623} 5,7-Dihydroxychromone (0.4, 2, and 10 µM) reduces increases in apoptosis and the levels of reactive oxygen species (ROS) induced by 6-OHDA (Item No. 25330) in SH-SY5Y neuroblastoma cells. It also increases the levels of HO-1, NQO1, and GCLc in SH-SY5Y cells when used at concentrations ranging from 0.08 to 10 µM.{48624}  

 

Available on backorder

SKU: 29006 - 5 mg Category:

Description

A flavone decomposition product; reduces radial growth of the soil pathogenic fungi R. solani and S. rolfsii (IC50s = 18 and 26 µM, respectively) but has no effect on soil pathogenic bacteria of the genus Bradyrhizobium; reduces increases in apoptosis and the levels of intracellular ROS induced by 6-OHDA at 0.4, 2, and 10 µM; increases the levels of HO-1, NQO1, and GCLc in SH-SY5Y neuroblastoma cells at 0.08-10 µM


Formal name: 5,7-dihydroxy-4H-1-benzopyran-4-one

Synonyms: 

Molecular weight: 178.1

CAS: 31721-94-5

Purity: ≥98%

Formulation: A crystalline solid