A mixture of 5-carboxy and 6-carboxy derivatives of fluorescein; used to label biomolecules through a reaction involving the carboxyl group; membrane impermeant

5(6)-Carboxyfluorescein – 1 g

Brand:
Cayman
CAS:
72088-94-9
Storage:
-20
UN-No:
Non-Hazardous - /

5(6)-Carboxyfluorescein is a mixture of 5-carboxy and 6-carboxy derivatives of fluorescein. It is commonly used to label biomolecules through a reaction involving the carboxyl group.{13893} Unlike its succinimidyl ester derivative CFSE (Item No. 14456), 5(6)-carboxyfluorescein is membrane impermeant. As a result, it can be used in studies of membrane permeability.{24235} 5(6)-Carboxyfluorescein displays excellent fluorescence (excitation/emission at 492/514 nm, respectively), and its excitation maximum closely matches the 488 nm spectral line of argon-ion lasers.  

 

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Description

A mixture of 5-carboxy and 6-carboxy derivatives of fluorescein; used to label biomolecules through a reaction involving the carboxyl group; membrane impermeant, with applications in studies of membrane permeability

Formal name: 3′,6′-dihydroxy-3-oxo-spiro[isobenzofuran-1(3H),9′-[9H]xanthene]-ar-carboxylic acid

Synonyms:  5(6)-FAM

Molecular weight: 376.3

CAS: 72088-94-9

Purity: ≥90%

Formulation: A crystalline solid

Application|Flow Cytometry||Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Research Area

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