An isomer of 17-phenyl trinor PGF2α ethyl amide wherein the double bond between carbons 5 and 6 has been changed from cis (Z) to trans (E); an impurity in commercial preparations of the bulk drug product

5-trans-17-phenyl trinor Prostaglandin F2α ethyl amide – 1 mg

Brand:
Cayman
CAS:
1163135-95-2
Storage:
-20
UN-No:
De Minimis - 1231 / 3

17-phenyl trinor Prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide) is an F-series PG analog which has been approved for use as an ocular hypotensive drug.{8941} 5-trans-17-phenyl trinor PGF2α ethyl amide is an isomer of 17-phenyl trinor PGF2α ethyl amide wherein the double bond between carbons 5 and 6 has been changed from cis (Z) to trans (E). The trans isomer of 17-phenyl trinor PGF2α ethyl amide occurs as an impurity in commercial preparations of the bulk drug product. The present compound was prepared primarily as an analytical standard for detection and quantitation of this impurity. From what can be inferred from the study of other trans isomers of F-type PGs, the biological activity of this isomer is likely to be similar to that of the cis isomer. However, there are no specific published reports on the biological activity of 5-trans-17-phenyl trinor PGF2α ethyl amide.  

 

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SKU: 10008132 - 1 mg Category:

Description

An isomer of 17-phenyl trinor PGF2α ethyl amide wherein the double bond between carbons 5 and 6 has been changed from cis (Z) to trans (E); an impurity in commercial preparations of the bulk drug product

Formal name: N-ethyl-9α,11α,15S-trihydroxy-17-phenyl-18,19,20-trinor-prosta-5E,13E-dien-1-amide

Synonyms:  5,6-trans-17-phenyl trinor PGF2α ethyl amide|5-trans Bimatoprost

Molecular weight: 415.6

CAS: 1163135-95-2

Purity: ≥98%

Formulation: A solution in methyl acetate

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Lipids|Prostaglandins||Product Type|Biochemicals|Pharmaceutical Impurities||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway

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