A stable

5-Octyl-α-ketoglutarate – 10 mg

Brand:
Cayman
CAS:
1616344-00-3
Storage:
-20
UN-No:
Non-Hazardous - /

In addition to its role in the Krebs cycle, α-ketoglutarate (2-oxoglutarate) has roles as a substrate or modulator of enzymes. 5-Octyl-α-ketoglutarate, also known as α-ketoglutarate octyl ester, is a stable, cell-permeable molecule that generates free α-ketoglutarate upon hydrolysis of the ester bond by cytoplasmic esterases.{21289} It is used in experiments to increase levels of intracellular α-ketoglutarate.{21289} 5-Octyl-α-ketoglutarate has been shown to modulate a variety of enzymes and signaling pathways, particularly in the context of glycolysis, hypoxia, and cancer.{21289,26774,27744,27745,26069}  

 

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Description

A stable, cell-permeable molecule that generates free α-ketoglutarate upon hydrolysis by cytoplasmic esterases; used in experiments to increase levels of intracellular α-ketoglutarate and modulate a variety of enzymes, particularly in the context of glycolysis, hypoxia, and cancer

Formal name: 2-oxo-pentanedioic acid, 5-octyl ester

Synonyms:  α-KG octyl ester

Molecular weight: 258.3

CAS: 1616344-00-3

Purity: ≥98%

Formulation: A film

Product Type|Biochemicals||Research Area|Cancer|Metabolism||Research Area|Cancer|Tumor Microenvironment||Research Area|Cell Biology|Mitochondrial Biology||Research Area|Endocrinology & Metabolism|Carbohydrate Metabolism||Research Area|Neuroscience|Cannabinoid Research|Endocannabinoids

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