A methoxyindole; synthesized in rat pineal gland

5-Methoxyindole-3-acetic acid – 1 g

Brand:
Cayman
CAS:
3471-31-6
Storage:
-20
UN-No:
Non-Hazardous - /

5-Methoxyindole-3-acetic acid (5-MIAA) is a methoxyindole that is synthesized in rat pineal gland, retina, and harderian gland.{46703} Following conversion to a peroxyl radical by horseradish peroxidase (HRP), 5-MIAA increases the rate of formation of thiobarbituric acid reactive substances (TBARS) in liposomes and is cytotoxic to V79 hamster cells.{46704,46705} In vivo, 5-MIAA (100 and 200 µg/animal) prolongs the estrous cycle and increases diestrous smears, uterine weight, the number of uterine follicles, and plasma levels of 17β-estradiol (Item No. 10006315) in female rats.{46703}  

 

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Description

A methoxyindole; synthesized in rat pineal gland, retina, and harderian gland; following conversion to a peroxyl radical by HRP, increases the rate of formation of TBARS in liposomes and is cytotoxic to V79 hamster cells; prolongs the estrous cycle and increases diestrous smears, uterine weight, the number of uterine follicles, and plasma levels of 17β-estradiol in female rats

Formal name: 5-methoxy-1H-indole-3-acetic acid

Synonyms:  5-Methoxy-IAA|5-Methoxyindoleacetic acid|5-MIAA

Molecular weight: 205.2

CAS: 3471-31-6

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Ox Stress Reagents||Research Area|Cell Biology|Cell Death||Research Area|Endocrinology & Metabolism|Reproductive Biology||Research Area|Oxidative Stress & Reactive Species|Lipid Peroxidation||Research Area|Oxidative Stress & Reactive Species|Pro-oxidant Activity

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