An internal standard for the quantification of 5-fluorouracil by GC- or LC-MS

5-Fluorouracil-13C,15N2 – 1 mg

Brand:
Cayman
CAS:
1189423-58-2
Storage:
-20
UN-No:
De Minimis - 2811 / 6.1

5-Fluorouracil-13C,15N2 is intended for use as an internal standard for the quantification of 5-flurouracil (Item No. 14416) by GC- or LC-MS. 5-Fluorouracil is a pyrimidine analog that irreversibly inhibits thymidylate synthase, blocking the synthesis of thymidine which is required for DNA synthesis. Intracellular metabolites of 5-fluorouracil exert cytotoxic effects by either inhibiting thymidylate synthetase, or through incorporation into RNA and DNA, ultimately initiating apoptosis.{18418}  

 

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SKU: 26683 - 1 mg Category:

Description

An internal standard for the quantification of 5-fluorouracil by GC- or LC-MS,

Formal name: 5-fluoro-2,4(1H,3H)-pyrimidinedione-2-13C-1,3-15N2

Synonyms:  5-FU-13C,15N2

Molecular weight: 133.1

CAS: 1189423-58-2

Purity: ≥95%

Formulation: A solid

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Isotopically Labeled Standards|13C||Product Type|Biochemicals|Isotopically Labeled Standards|15N||Product Type|Biochemicals|Small Molecule Inhibitors|Nucleic Acid Turnover/Signaling||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Cancer|DNA Damage and Repair

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