A thymidine analog that is readily incorporated

5-Chloro-2′-deoxyuridine – 50 mg

Brand:
Cayman
CAS:
50-90-8
Storage:
-20
UN-No:
Non-Hazardous - /

5-Chloro-2′-deoxyuridine (CldU) is a thymidine analog that is readily incorporated, following phosphorylation, into newly synthesized DNA in place of thymidine.{29384} Like 5-bromo-2’-deoxyuridine (Item No. 15580) and 5-iodo-2’-deoxyuridine, CldU can be detected immunologically in cells and tissues.{29386,29381} CldU can also be added to cells or tissues sequentially with another thymidine analog to label temporally distinct populations.{29383,29385} The insertion of thymidine analogs, including CldU, can significantly alter DNA processing and replication, so these analogs have also been used as mutagens, clastogens, and antiviral compounds.{29384,29382}  

 

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Description

A thymidine analog that is readily incorporated, following phosphorylation, into newly synthesized DNA in place of thymidine; can be detected immunologically in cells and tissues

Formal name: 5-chloro-2′-deoxy-uridine

Synonyms:  Chlorodeoxyuridine|CldU

Molecular weight: 262.6

CAS: 50-90-8

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Labeling & Detection|Dyes, Stains, & Indicators||Research Area|Cell Biology|Cell Cycle||Research Area|Epigenetics, Transcription, & Translation|RNA, DNA, & Protein Synthesis

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