A high-affinity ligand of CB2 (Ki = 8.5 nM) with little affinity for CB1 (Ki >10

4-Quinolone-3-Carboxamide Furan CB2 Agonist – 5 mg

Brand:
Cayman
CAS:
1314230-75-5
Storage:
-20
UN-No:
Non-Hazardous - /

Agonists of the peripheral cannabinoid (CB) receptor CB2 may have antinociceptive and anti-inflammatory effects, as well as prevent osteoporosis.{16338,13862} 4-Quinolone-3-carboxamide Furan CB2 Agonist is a high-affinity ligand of CB2 (Ki = 8.5 nM) with little affinity for CB1 (Ki >10,000 nM).{20020} This compound demonstrates antinociceptive efficacy in the mouse formalin test at 1 mg/kg, an action which is blocked by a CB2-selective antagonist, AM630 (Item No. 10006974).{20020}  

 

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SKU: 11094 - 5 mg Category:

Description

A high-affinity ligand of CB2 (Ki = 8.5 nM) with little affinity for CB1 (Ki >10,000 nM); demonstrates antinociceptive efficacy in the mouse formalin test at 1 mg/kg, an action which is blocked by a CB2-selective antagonist, AM630

Formal name: 6-(2-furanyl)-1,4-dihydro-8-methoxy-4-oxo-1-pentyl-N-tricyclo[3.3.1.13,7]dec-1-yl-3-quinolinecarboxamide

Synonyms:  4Q3C CB2 Agonist

Molecular weight: 488.6

CAS: 1314230-75-5

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Neuroscience|Cannabinoid Research|CB1 & CB2 Receptors||Research Area|Neuroscience|Pain Research

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