4-oxo-2-Nonenal Alkyne – 100 µg

Brand:
Cayman
CAS:
1680193-58-1
Storage:
-80
UN-No:
De Minimis - 1231 / 3

4-oxo-2-Nonenal (4-ONE, Item No. 10185) is a product of lipid peroxidation that actively modifies histidine and lysine residues on proteins and causes protein cross-linking.{9278,11422,11421,11420,11419} It also modifies 2′-deoxyguanosine, further implicating lipid peroxidation in mutagenesis and carcinogenesis.{9278} 4-ONE alkyne is an alkyne-tagged electrophile that can be used as a probe to isolate and identify the reaction products of lipid peroxidation using click chemistry.{26588,26526}  

 

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Description

An alkyne-tagged electrophile that can be used as a probe to isolate and identify the reaction products of lipid peroxidation using click chemistry


Formal name: (E)-4-oxonon-2-en-8-ynal

Synonyms:  4-ONE Alkyne|Alkynyl 4-oxo-2-Nonenal|Click Tag™ 4-oxo-2-Nonenal Alkyne

Molecular weight: 150.2

CAS: 1680193-58-1

Purity: ≥98%

Formulation: A solution in methyl acetate


Application|Click Chemistry||Product Type|Biochemicals|Labeling & Detection|Reactive Probes||Research Area|Oxidative Stress & Reactive Species|Lipid Peroxidation