Description
A fluorogenic substrate for α-L-iduronidase, an enzyme found in cell lysosomes that is involved in the degradation of glycosaminoglycans; cleaved by α-L-iduronidase to release the fluorescent moiety 4-MU; ex = 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively; em = 445-455 nm, increasing as pH decreases
Formal name: 4-methyl-2-oxo-2H-1-benzopyran-7-yl α-L-idopyranosiduronic acid
Synonyms: 4-Methylumbelliferyl-α-L-Idopyranosiduronic Acid|4-MU-α-IdoA|MU-α-IdoA
Molecular weight: 352.3
CAS: 66966-09-4
Purity: ≥90%
Formulation: A crystalline solid
Application|Enzyme Activity||Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Enzyme Substrates||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Research Area|Cell Biology|Endomembrane System & Vesicular Trafficking||Research Area|Endocrinology & Metabolism|Carbohydrate Metabolism
