A fluorogenic substrate of α-galactosidase

4-Methylumbelliferyl-α-D-Galactopyranoside – 10 mg

Brand:
Cayman
CAS:
38597-12-5
Storage:
-20
UN-No:
Non-Hazardous - /

4-Methylumbelliferyl-α-D-galactopyranoside (4-MU-α-Gal) is a fluorogenic substrate of α-galactosidase.{33136,33137} In addition to its use in characterizing novel α-galactosidases, 4-MU-α-Gal is used in assays to evaluate deficiency in α-galactosidase activity related to Fabry disease.{33138} Hydrolysis of 4-MU-α-Gal releases the fluorescent product 4-MU, which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively.{27251}  

 

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Description

A fluorogenic substrate of α-galactosidase

Formal name: 7-(α-D-galactopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one

Synonyms:  4-MU-α-Gal|MU-α-Gal

Molecular weight: 338.3

CAS: 38597-12-5

Purity: ≥98%

Formulation: A crystalline solid

Application|Enzyme Activity||Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Enzyme Substrates||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Research Area|Endocrinology & Metabolism|Inborn Errors of Metabolism||Research Area|Neuroscience

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