An ultraviolet light blocker used in cosmetics and sunscreen preparations that also has estrogenic activities

4-Methylbenzylidene camphor – 10 g

Brand:
Cayman
CAS:
36861-47-9
Storage:
-20
UN-No:
Non-Hazardous - /

4-Methylbenzylidene camphor is an ultraviolet light blocker used in cosmetics and sunscreen preparations that also has estrogenic activities.{20419,20420} It has estrogenic activity in fish and in mammals, binding competitively to estrogen receptors and stimulating transactivation.{20419} In addition to reducing receptor sensitivity to estradiol, 4-MBC directs dose-dependent changes in the expression of estrogen receptor subtypes, progesterone receptor, and androgen receptor.{20419,20420} This results in changes in reproductive organ and brain development in both males and females.{20419,20420} When applied topically, it is absorbed systemically and can be detected in urine.{20421}  

 

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Description

An ultraviolet light blocker used in cosmetics and sunscreen preparations that also has estrogenic activities, binding competitively to estrogen receptors and stimulating transactivation; changes reproductive organ and brain development in both males and females

Formal name: 1,7,7-trimethyl-3-[(4-methylphenyl)methylene]-bicyclo[2.2.1]heptan-2-one

Synonyms:  4-MBC|Enzacamene|Eusolex 6300|Neo Heliopan MBC|Parsol 500|Uvinul MBC 95

Molecular weight: 254.4

CAS: 36861-47-9

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals||Research Area|Endocrinology & Metabolism|Hormones & Receptors|Androgens||Research Area|Endocrinology & Metabolism|Hormones & Receptors|Estrogens & Progestins||Research Area|Endocrinology & Metabolism|Reproductive Biology||Research Area|Toxicology|Environmental|Aquatic Systems||Research Area|Toxicology|Environmental|Endocrine Disruption

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