Description
An aglycone form of gastrodin; inhibits LPS-induced NO and ROS production and decreases iNOS levels in RAW 264.7 cells at 0.5 and 1 mM; reduces exudate volume and leukocyte infiltration in a rat model of carrageenan-induced air pouch inflammation at 1.5 and 4.5 mg/animal; inhibits acetic acid-induced writhing in mice at 50 and 100 mg/kg; reduces infarct volume and the number of TUNEL-positive neurons in the ipsilateral cortex in a rat model of focal cerebral ischemia induced by transient MCAO at 50 mg/kg; increases the number of entries into, and the percentage of time spent in, the open arms of the elevated plus maze in mice at 50 and 100 mg/kg
Formal name: 4-hydroxy-benzenemethanol
Synonyms: p-Hydroxybenzyl Alcohol|NSC 227926
Molecular weight: 124.1
CAS: 623-05-2
Purity: ≥98%
Formulation: A crystalline solid