A metabolite of atorvastatin; formed by metabolism of atorvastatin by CYP3A4

4-hydroxy Atorvastatin (calcium salt) – 500 µg

Brand:
Cayman
CAS:
265989-44-4
Storage:
-20
UN-No:
Non-Hazardous - /

4-hydroxy Atorvastatin is a metabolite of atorvastatin (Item No. 10493), an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias.{18329,18240,18241,18235} Atorvastatin is metabolized by the cytochrome P450 (CYP) isoform CYP3A4 to form 4-hydroxy atorvastatin.{18329}  

 

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Description

A metabolite of atorvastatin; formed by metabolism of atorvastatin by CYP3A4

Formal name: 2-(4-fluorophenyl)-βR,δR-dihydroxy-4-[[(4-hydroxyphenyl)amino]carbonyl]-5-(1-methylethyl)-3-phenyl-1H-pyrrole-1-heptanoic acid, hemicalcium salt

Synonyms:  p-hydroxy Atorvastatin|para-hydroxy Atorvastatin

Molecular weight: 593.7

CAS: 265989-44-4

Purity: ≥90%

Formulation: A crystalline solid

Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Cardiovascular System|Lipids & Lipoproteins|Cholesterol Metabolism||Research Area|Lipid Biochemistry|Sterol Lipids||Research Area|Toxicology|Drug Metabolism|Cytochrome P450||Research Area|Toxicology|Drug Metabolism|Drug Metabolites

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